CaSR, or Calcium-Sensing Receptor, antagonists are a class of pharmaceuticals that act on the CaSR receptor, a critical player in regulating calcium levels in the body. By inhibiting the CaSR, these drugs can help manage disorders such as hypoparathyroidism and prevent excessive calcium excretion. CaSR antagonists work by increasing parathyroid hormone levels, which enhances calcium reabsorption in the kidneys and bones. This balancing act is vital for individuals with conditions that disrupt calcium homeostasis. These antagonists exemplify how pharmaceuticals can fine-tune the body's intricate biochemical processes.
