(alphaS)-alpha-Methyl-4-(4-methyl-5-thiazolyl)benzenemethanamine hydrochloride (1:1)
[CAS# 1948273-01-5]

Identification

• Classification: Chemical reagent >> Organic reagent >> Amine salt (ammonium salt)
• Name: (alphaS)-alpha-Methyl-4-(4-methyl-5-thiazolyl)benzenemethanamine hydrochloride (1:1)
• Synonyms: (S)-1-(4-(4-Methylthiazol-5-yl)phenyl)ethanamine hydrochloride
• Molecular Formula: C₁₂H₁₄N₂S^.HCl
• Molecular Weight: 254.78
• CAS Registry Number: 1948273-01-5
• SMILES: CC1=C(SC=N1)C2=CC=C(C=C2)[C@H](C)N.Cl

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P305+P351+P338

Discovory and Applicatios

(alphaS)-alpha-Methyl-4-(4-methyl-5-thiazolyl)benzenemethanamine hydrochloride (1:1) is a chemical compound with the molecular formula C11H14N2S·HCl. This compound belongs to the class of substituted phenylethylamines, and it contains both a thiazole ring and a benzene ring as part of its structure. The compound has been studied primarily in the context of its pharmacological properties.

The structure of (alphaS)-alpha-Methyl-4-(4-methyl-5-thiazolyl)benzenemethanamine hydrochloride includes a methyl group at the alpha position relative to the amine group, a thiazole ring attached to the benzene ring at the 4-position, and the amine functional group that classifies it as an aromatic amine. These structural features suggest that the compound may interact with certain biological targets, and its hydrochloride form helps to stabilize the molecule and increase its solubility in aqueous environments.

Research into compounds of this class, such as (alphaS)-alpha-Methyl-4-(4-methyl-5-thiazolyl)benzenemethanamine hydrochloride, has been linked to studies in medicinal chemistry, particularly concerning their potential as drug candidates. Compounds with thiazole rings, in particular, are well-known for their broad spectrum of biological activities, including antimicrobial, antifungal, and anticancer properties.

As of now, specific documented applications of (alphaS)-alpha-Methyl-4-(4-methyl-5-thiazolyl)benzenemethanamine hydrochloride in pharmaceutical products or therapies are not widely reported in the literature. However, similar compounds have been explored for their therapeutic potential, and derivatives of substituted phenylethylamines have been investigated in a variety of contexts, including as central nervous system stimulants, for mood disorders, and in some cases, as substrates in the synthesis of more complex drug molecules.

The compound's synthesis, characterization, and potential bioactivity are topics of ongoing research, particularly in the context of optimizing its pharmacological properties. While (alphaS)-alpha-Methyl-4-(4-methyl-5-thiazolyl)benzenemethanamine hydrochloride may not yet have widespread commercial applications, its structure suggests it could be a useful building block in the design of new therapeutic agents. Further studies are needed to establish its biological activity and explore its full potential in medicinal chemistry.

References

(2021). Compounds and methods for targeted degradation of kras. WO-2021207172-A1, 2021-10-14.
Priority Date: 2020-04-06.

(2021). Smarca2-vhl degraders. WO-2021142247-A1, 2021-07-15.
Priority Date: 2020-01-10.

(2021). Compounds and methods for the targeted degradation of interleukin-1 receptor-associated kinase 1 proteins. WO-2021018118-A1, 2021-02-04.
Priority Date: 2019-07-29.