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4-Bromo-7-azaindole
[CAS# 348640-06-2]

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Identification
Classification Organic raw materials >> Heterocyclic compound
Name 4-Bromo-7-azaindole
Synonyms 4-Bromo-1H-pyrrolo[2,3-b]pyridine
Molecular Structure CAS # 348640-06-2, 4-Bromo-7-azaindole, 4-Bromo-1H-pyrrolo[2,3-b]pyridine
Molecular Formula C7H5BrN2
Molecular Weight 197.03
CAS Registry Number 348640-06-2
EC Number 625-999-6
SMILES C1=CNC2=NC=CC(=C21)Br
Properties
Solubility 1042 mg/L (25 ºC water)
Density 1.8±0.1 g/cm3, Calc.*
Index of Refraction 1.728, Calc.*
Melting point 89.48 ºC
Boiling Point 300.14 ºC
* Calculated using Advanced Chemistry Development (ACD/Labs) Software.
Safety Data
Hazard Symbols symbol symbol symbol   GHS05;GHS06;GHS07 Danger    Details
Hazard Statements H301-H315-H318-H335    Details
Precautionary Statements P261-P264-P264+P265-P270-P271-P280-P301+P316-P302+P352-P304+P340-P305+P354+P338-P317-P319-P321-P330-P332+P317-P362+P364-P403+P233-P405-P501    Details
Hazard Classification
up    Details
HazardClassCategory CodeHazard Statement
Skin irritationSkin Irrit.2H315
Specific target organ toxicity - single exposureSTOT SE3H335
Serious eye damageEye Dam.1H318
Acute toxicityAcute Tox.3H301
Acute toxicityAcute Tox.4H302
Eye irritationEye Irrit.2H319
Acute toxicityAcute Tox.4H332
Acute toxicityAcute Tox.4H312
SDS Available
up Discovory and Applicatios
4-Bromo-7-azaindole is a specialized heterocyclic compound that combines a bromine atom with an azaindole ring structure. This compound is notable for its unique chemical properties and diverse applications in various scientific fields.

The discovery of 4-bromo-7-azaindole stems from research into halogenated heterocycles, which are valuable in both organic synthesis and medicinal chemistry. The bromine atom is positioned at the 4-position of the azaindole ring, which includes a nitrogen atom integrated into an indole-like structure. This configuration imparts distinctive electronic and steric properties to the molecule, enhancing its reactivity and utility.

In medicinal chemistry, 4-bromo-7-azaindole is used as a key intermediate in the synthesis of pharmaceutical compounds. Its ability to participate in various chemical reactions makes it a valuable building block for developing new drug candidates. Derivatives of 4-bromo-7-azaindole have been investigated for their potential as therapeutic agents, including kinase inhibitors that target specific enzymes involved in cancer and other diseases.

The compound also finds applications in material science. The presence of the bromine atom provides a reactive site that can be exploited in the synthesis of functionalized polymers and materials. These materials often exhibit enhanced properties, such as improved stability and specific chemical reactivity, making them suitable for use in advanced electronic devices, sensors, and other specialized applications.

Moreover, 4-bromo-7-azaindole is utilized in chemical research as a reagent. Its unique structure allows researchers to explore new synthetic pathways and develop innovative compounds. The compound serves as a valuable tool in the study of chemical reactions and the design of complex organic molecules.
Market Analysis Reports
List of Reports Available for 4-Bromo-7-azaindole
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