(R)-Ambrisentan
[CAS# 1007358-76-0]

Identification

• Name: (R)-Ambrisentan
• Synonyms: (2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
• Molecular Formula: C₂₂H₂₂N₂O₄
• Molecular Weight: 378.42
• CAS Registry Number: 1007358-76-0
• SMILES: CC1=CC(=NC(=N1)O[C@@H](C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)C

Properties

• Solubility: 2.561 mg/L (25 °C water)
• Density: 1.2±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.593, Calc.^*
• Melting point: 218.04 °C
• Boiling Point: 511.65 °C, 551.1±60.0 °C (760 mmHg), Calc.^*
• Flash Point: 287.1±32.9 °C, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H302+H312+H332-H315-H319
• Safety Statements: P261-P271-P280-P302+P352-P305+P351+P338