Hydroxy bendamustine
[CAS# 109882-27-1]

Identification

• Name: Hydroxy bendamustine
• Synonyms: 4-[5-[2-chloroethyl(2-hydroxyethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
• Molecular Formula: C₁₆H₂₂ClN₃O₃
• Molecular Weight: 339.82
• CAS Registry Number: 109882-27-1
• EC Number: 807-636-5
• SMILES: CN1C2=C(C=C(C=C2)N(CCO)CCCl)N=C1CCCC(=O)O

Properties

• Solubility: 126.1 mg/L (25 °C water)
• Density: 1.3±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.602, Calc.^*
• Melting point: 238.44 °C
• Boiling Point: 555.33 °C, 608.5±55.0 °C (760 mmHg), Calc.^*
• Flash Point: 321.8±31.5 °C, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS06;GHS08 Danger
• Risk Statements: H301-H341-H351-H360
• Safety Statements: P203-P260-P264-P270-P280-P281-P301+P316-P318-P319-P321-P330-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Carcinogenicity	Carc.	1A	H350
Acute toxicity	Acute Tox.	3	H301
Specific target organ toxicity - repeated exposure	STOT RE	1	H372
Germ cell mutagenicity	Muta.	1B	H340
Reproductive toxicity	Repr.	1B	H360