(+)-Griseofulvin
[CAS# 126-07-8]

Identification

• Classification: API >> Antibiotics >> Other antibiotics
• Name: (+)-Griseofulvin
• Synonyms: (2S)-trans-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2[3H],1'-[2]cyclohexene)-3,4'-dione
• Molecular Formula: C₁₇H₁₇ClO₆
• Molecular Weight: 352.77
• CAS Registry Number: 126-07-8
• EC Number: 204-767-4

Properties

• Melting point: 217-224 °C
• alpha: 354 ° (c=1, dimethylform)
• Water solubility: practically insoluble

Safety Data

• Hazard Symbols: T
• Risk Statements: R60;R61;R40;R43
• Safety Statements: S53;S22;S36/37/39;S45

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Carcinogenicity	Carc.	2	H351
Reproductive toxicity	Repr.	1B	H360
Skin sensitization	Skin Sens.	1	H317
Germ cell mutagenicity	Muta.	2	H341
Germ cell mutagenicity	Muta.	1B	H340
Reproductive toxicity	Repr.	1A	H360
Chronic hazardous to the aquatic environment	Aquatic Chronic	2	H411
Acute toxicity	Acute Tox.	4	H302
Acute toxicity	Acute Tox.	4	H332
Carcinogenicity	Carc.	1B	H350
Specific target organ toxicity - single exposure	STOT SE	2	H371
Specific target organ toxicity - repeated exposure	STOT RE	2	H373