2-(2-(2-Aminoethoxy)ethoxy)acetic acid hydrochloride
[CAS# 134979-01-4]

Identification

• Classification: Surfactant >> Anionic surfactant >> Fatty acid salt type
• Name: 2-(2-(2-Aminoethoxy)ethoxy)acetic acid hydrochloride
• Molecular Formula: C₆H₁₃NO₄.HCl
• Molecular Weight: 199.63
• CAS Registry Number: 134979-01-4
• EC Number: 816-400-0
• SMILES: C(COCCOCC(=O)O)N.Cl

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H302-H315-H319-H335
• Safety Statements: P261-P305+P351+P338

Discovery and Applications

2-(2-(2-Aminoethoxy)ethoxy)acetic acid hydrochloride, also known as AEAA hydrochloride, is a hydrochloride salt of a compound with significant relevance in medicinal chemistry and biochemistry. This substance features a complex structure characterized by a branched ether chain and an amino group, which endows it with a variety of biological activities and applications.

The discovery of 2-(2-(2-Aminoethoxy)ethoxy)acetic acid hydrochloride can be traced to research endeavors focused on amino acids and their derivatives. In the quest for compounds that exhibit diverse biological effects, scientists synthesized this compound to explore its potential applications in pharmaceuticals and biochemical research. The incorporation of an amino group within its structure has been a pivotal aspect of its design, contributing to its interaction with biological targets.

AEAA hydrochloride finds several applications primarily within the pharmaceutical industry. Its structure allows for modifications that enhance its efficacy and selectivity towards specific biological pathways. This characteristic is particularly significant in the design of drug candidates aimed at treating neurological disorders, where the ability to penetrate the blood-brain barrier is crucial for therapeutic success.

In addition to its pharmaceutical applications, 2-(2-(2-Aminoethoxy)ethoxy)acetic acid hydrochloride serves as a valuable biochemical probe. Its similarity to natural amino acids enables researchers to utilize AEAA hydrochloride in studying protein interactions and enzyme activities. This application is vital in unraveling the mechanisms underlying various biochemical processes and developing targeted therapeutic strategies.

Moreover, the compound is explored for its potential as a chelating agent due to its amino group, which can effectively interact with metal ions. This property has significant implications in coordination chemistry, where AEAA hydrochloride may be used in the development of metal-based therapeutic agents. Such applications extend to diagnosing and treating metal overload conditions, as well as enhancing the efficacy of chemotherapeutic agents through metal complexation.

The stability and aqueous solubility of AEAA hydrochloride also make it a suitable candidate for formulation in various drug delivery systems. This characteristic is essential for ensuring the bioavailability of therapeutic agents, particularly those intended for parenteral administration.

Research continues to explore the full potential of 2-(2-(2-Aminoethoxy)ethoxy)acetic acid hydrochloride in various applications, emphasizing its role in advancing medicinal chemistry. As scientists investigate amino acid derivatives further, the importance of AEAA hydrochloride in developing novel therapeutic agents and understanding complex biological systems becomes increasingly clear.

In summary, 2-(2-(2-Aminoethoxy)ethoxy)acetic acid hydrochloride is a versatile compound with significant applications in pharmaceuticals, biochemical research, and coordination chemistry. Its discovery has contributed to the broader field of amino acid derivatives, underscoring the importance of this compound in ongoing drug discovery efforts and the exploration of biological mechanisms.

References

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