10-(1-Azabicyclo[2.2.2]Oct-3-Ylmethyl)-10H-Phenothiazine
[CAS# 147780-50-5]

Identification

• Name: 10-(1-Azabicyclo[2.2.2]Oct-3-Ylmethyl)-10H-Phenothiazine
• Synonyms: (R)-(+)-Mequitazine; 10-(1-azabicyclo(2.2.2)oct-8-ylmethyl)phenothiazine; 10-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-10H-phenothiazin
• Molecular Formula: C₂₀H₂₂N₂S
• Molecular Weight: 322.47
• CAS Registry Number: 147780-50-5
• SMILES: C1CN2CCC1C(C2)CN3C4=CC=CC=C4SC5=CC=CC=C53
• InChI: 1S/C20H22N2S/c1-3-7-19-17(5-1)22(18-6-2-4-8-20(18)23-19)14-16-13-21-11-9-15(16)10-12-21/h1-8,15-16H,9-14H2
• InChIKey: HOKDBMAJZXIPGC-UHFFFAOYSA-N

Properties

• Density: 1.3±0.1g/cm³ (Cal.)
• Boiling point: 469.4±24.0°C at 760 mmHg (Cal.)
• Flash point: 237.7±22.9°C (Cal.)
• Refractive index: 1.707 (Cal.)

References

• (1): Manthena V. S. Varma, Khandavilli Sateesh, and Ramesh Panchagnula. Functional Role of P-Glycoprotein in Limiting Intestinal Absorption of Drugs: Contribution of Passive Permeability to P-Glycoprotein Mediated Efflux Transport, Mol. Pharmaceutics 2005, 2(1), 12-21.