7-Methyl-7,8-Dihydroguanosine
[CAS# 15313-37-8]

Identification

• Classification: Biochemical >> Nucleoside drugs >> Nucleoside intermediate
• Name: 7-Methyl-7,8-Dihydroguanosine
• Synonyms: guanosine, N⁷-methyl-; InChI=1/C11H17N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h4,6-7,10,17-19H,2-3H2,1H3,(H3,12,13,14,20)/t4-,6-,7-,10-/m1/s1/f/h14H,12H2; N7-Methylguanosine
• Molecular Formula: C₁₁H₁₇N₅O₅
• Molecular Weight: 299.28
• CAS Registry Number: 15313-37-8
• SMILES: CN1CN(C2=C1C(=O)NC(=N2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
• InChI: 1S/C11H17N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h4,6-7,10,17-19H,2-3H2,1H3,(H3,12,13,14,20)/t4-,6-,7-,10-/m1/s1
• InChIKey: ZBDDPUHBOFHFRK-KQYNXXCUSA-N

Properties

• Density: 2.0±0.1g/cm³ (Cal.)
• Refractive index: 1.86 (Cal.)

References

• (1): Malwina StrenkowskaThese authors contributed equally to this work., Joanna Kowalska, Maciej Lukaszewicz, Joanna Zuberek, Wei Su, Robert E. Rhoads, Edward Darzynkiewicz and Jacek Jemielity. Towards mRNA with superior translational activity: synthesis and properties of ARCA tetraphosphates with single phosphorothioate modifications, New J. Chem., 2010, 34, 993.