(4R)-4-[(1Z,5E,7E,11R)-11-Methoxy-8-Methyltetradeca-1,5,7,13-Tetraenyl]-2-[(1R,2S)-2-Methylcyclopropyl]-4,5-Dihydro-1,3-Thiazole
[CAS# 155233-30-0]

Identification

• Name: (4R)-4-[(1Z,5E,7E,11R)-11-Methoxy-8-Methyltetradeca-1,5,7,13-Tetraenyl]-2-[(1R,2S)-2-Methylcyclopropyl]-4,5-Dihydro-1,3-Thiazole
• Synonyms: (4R)-4-[(1Z,5E,7E,11R)-11-Methoxy-8-Methyl-Tetradeca-1,5,7,13-Tetraenyl]-2-[(1R,2S)-2-Methylcyclopropyl]-4,5-Dihydrothiazole; (4R)-4-[(1Z,5E,7E,11R)-11-Methoxy-8-Methyltetradeca-1,5,7,13-Tetraenyl]-2-[(1R,2S)-2-Methylcyclopropyl]-4,5-Dihydrothiazole; (4R)-4-[(1Z,5E,7E,11R)-11-Methoxy-8-Methyl-Tetradeca-1,5,7,13-Tetraenyl]-2-[(1R,2S)-2-Methylcyclopropyl]-4,5-Dihydro-1,3-Thiazole
• Molecular Formula: C₂₃H₃₅NOS
• Molecular Weight: 373.60
• CAS Registry Number: 155233-30-0
• SMILES: [C@@H]1([C@H](C1)C)C2=N[C@@H](CS2)\C=C/CC/C=C/C=C(/CC[C@@H](OC)CC=C)C
• InChI: 1S/C23H35NOS/c1-5-11-21(25-4)15-14-18(2)12-9-7-6-8-10-13-20-17-26-23(24-20)22-16-19(22)3/h5,7,9-10,12-13,19-22H,1,6,8,11,14-17H2,2-4H3/b9-7+,13-10-,18-12+/t19-,20+,21-,22+/m0/s1
• InChIKey: LUEYTMPPCOCKBX-KWYHTCOPSA-N

Properties

• Density: 1.015g/cm³ (Cal.)
• Boiling point: 471.744°C at 760 mmHg (Cal.)
• Flash point: 239.102°C (Cal.)

References

• (1): James C. Muir, Gerald Pattenden and Tao Ye. Total synthesis of (+)-curacin A, a novel antimitotic metabolite from a cyanobacterium, J. Chem. Soc., Perkin Trans. 1, 2002, 0, 2243.