1-(5-Methylpyrazin-2-yl)methanamine dihydrochloride
[CAS# 2227206-03-1]

Identification

• Classification: Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Pyrazines
• Name: 1-(5-Methylpyrazin-2-yl)methanamine dihydrochloride
• Synonyms: (5-methylpyrazin-2-yl)methanamine;dihydrochloride
• Molecular Formula: C₆H₁₁Cl₂N₃
• Molecular Weight: 196.08
• CAS Registry Number: 2227206-03-1
• EC Number: 896-154-9
• SMILES: CC1=CN=C(C=N1)CN.Cl.Cl

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H302-H315-H319-H335
• Safety Statements: P261-P264-P264+P265-P270-P271-P280-P301+P317-P302+P352-P304+P340-P305+P351+P338-P319-P321-P330-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Specific target organ toxicity - single exposure	STOT SE	3	H335
Eye irritation	Eye Irrit.	2A	H319
Skin irritation	Skin Irrit.	2	H315
Acute toxicity	Acute Tox.	4	H302

Discovery and Applications

1-(5-Methylpyrazin-2-yl)methylamine dihydrochloride is a compound with important applications in drug development. This dihydrochloride derivative has attracted much attention due to its unique structure and potential therapeutic properties.

The synthesis and characterization of 1-(5-methylpyrazin-2-yl)methylamine dihydrochloride was first reported in the literature by researchers, providing detailed information about its chemical synthesis and structural elucidation. Initial studies focused on optimizing the synthetic route to produce the dihydrochloride salt, which is critical for its stability and solubility in aqueous environments.

1-(5-Methylpyrazin-2-yl)methylamine dihydrochloride has a stable pyrazine core with a methyl group at the 5 position and an amine functional group attached to the methylene bridge. The dihydrochloride form enhances its water solubility and bioavailability, facilitating its use in pharmaceutical formulations.

The compound shows promise as a potential candidate for drug development in medicinal chemistry. Researchers are exploring its pharmacological activities, including antibacterial and antiviral properties, which are critical for combating infectious diseases.

1-(5-Methylpyrazin-2-yl)methanamine dihydrochloride is a valuable tool in chemical biology research. It is used as a precursor for the synthesis of molecular probes and inhibitors targeting specific biological pathways, which facilitates the study of complex cellular processes.

Ongoing research aims to expand the applications of 1-(5-methylpyrazin-2-yl)methanamine dihydrochloride. The research focuses on further elucidating its mechanism of action, optimizing its synthesis for large-scale production, and exploring new therapeutic applications in fields such as neuroscience and oncology.

References

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