Gentamicin C1a
[CAS# 26098-04-4]

Identification

• Name: Gentamicin C1a
• Synonyms: (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-Diamino-3-[(2R,3R,6S)-3-Amino-6-(Aminomethyl)Tetrahydropyran-2-Yl]Oxy-2-Hydroxy-Cyclohexoxy]-5-Methyl-4-Methylamino-Tetrahydropyran-3,5-Diol; (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-Diamino-3-[[(2R,3R,6S)-3-Amino-6-(Aminomethyl)-2-Tetrahydropyranyl]Oxy]-2-Hydroxycyclohexoxy]-5-Methyl-4-Methylaminotetrahydropyran-3,5-Diol; (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-Diamino-3-[(2R,3R,6S)-3-Amino-6-(Aminomethyl)Oxan-2-Yl]Oxy-2-Hydroxy-Cyclohexyl]Oxy-5-Methyl-4-Methylamino-Oxane-3,5-Diol
• Molecular Formula: C₁₉H₃₉N₅O₇
• Molecular Weight: 449.55
• CAS Registry Number: 26098-04-4
• SMILES: [C@@]3(C)(O)CO[C@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]1O[C@H](CN)CC[C@H]1N)[C@@H]2O)[C@H](O)[C@H]3NC
• InChI: 1S/C19H39N5O7/c1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17/h8-18,24-27H,3-7,20-23H2,1-2H3/t8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-/m0/s1
• InChIKey: VEGXETMJINRLTH-BOZYPMBZSA-N

Properties

• Density: 1.4±0.1g/cm³ (Cal.)
• Boiling point: 675.2±55.0°C at 760 mmHg (Cal.)
• Flash point: 362.1±31.5°C (Cal.)

References

• (1): Feldman et al.. Aminoglycoside Activity Observed on Single Pre-translocation Ribosome Complexes, Nature Chemical Biology, 2009