2-Chloro-3,3,3-trifluoropropene
[CAS# 2730-62-3]

Identification

• Classification: Organic raw materials >> Organic fluorine compound
• Name: 2-Chloro-3,3,3-trifluoropropene
• Synonyms: 2-Chloro-3,3,3-trifluoro-1-propene
• Molecular Formula: C₃H₂ClF₃
• Molecular Weight: 130.50
• CAS Registry Number: 2730-62-3
• EC Number: 689-202-3
• SMILES: C=C(C(F)(F)F)Cl

Properties

• Density: 1.3±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.335, Calc.^*
• Boiling Point: 27.7±35.0 °C (760 mmHg), Calc.^*, 14-15 (°C (Expl.)
• Flash Point: -15.6±17.9 °C, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS02;GHS04;GHS07 Danger
• Risk Statements: H224-H280-H315-H319-H335
• Safety Statements: P210-P233-P240-P241-P242-P243-P261-P264-P264+P265-P271-P280-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P319-P321-P332+P317-P337+P317-P362+P364-P370+P378-P403+P233-P403+P235-P405-P410+P403-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Gases under pressure (liquid)	Press. Gas (Liq.)		H280
Flammable liquids	Flam. Liq.	1	H224
Eye irritation	Eye Irrit.	2	H319
Specific target organ toxicity - single exposure	STOT SE	3	H335
Skin irritation	Skin Irrit.	2	H315

• Transport Information: UN 1956

Discovery and Applications

2-Chloro-3,3,3-trifluoropropene (C₃H₂ClF₃) is an organofluorine compound belonging to the class of halogenated olefins. It contains a chlorine atom and three fluorine atoms attached to a propene backbone, making it structurally related to other fluorinated alkenes used in industrial applications. This compound is known for its role as an intermediate in the synthesis of fluorinated materials and other specialty chemicals.

The synthesis of 2-chloro-3,3,3-trifluoropropene typically involves halogenation and fluorination reactions of hydrocarbon precursors. Fluorination is achieved using fluorinating agents such as hydrogen fluoride (HF) or metal fluorides under controlled conditions. These reactions are designed to selectively introduce fluorine atoms while maintaining the desired molecular structure. Due to the high reactivity of fluorine, specialized equipment and reaction conditions are necessary to ensure controlled synthesis and high purity.

2-Chloro-3,3,3-trifluoropropene has found application in the development of fluorinated polymers, agrochemicals, and refrigerants. Fluorinated olefins serve as key intermediates in the production of polymeric materials with desirable properties such as high thermal stability, chemical resistance, and low surface energy. These properties make them valuable in coatings, films, and industrial components requiring durability in harsh environments.

Another important application of 2-chloro-3,3,3-trifluoropropene is in the synthesis of hydrofluoroolefin (HFO)-based refrigerants. HFOs are developed as alternatives to hydrofluorocarbons (HFCs) due to their lower global warming potential (GWP) and improved environmental performance. The presence of the double bond in fluorinated olefins allows for controlled reactivity, making them suitable precursors in the production of environmentally friendly refrigerants.

Handling of 2-chloro-3,3,3-trifluoropropene requires adherence to safety protocols due to its reactivity and potential hazards. Halogenated alkenes can exhibit toxicity and require appropriate storage conditions, including sealed containers and controlled temperatures, to prevent degradation. Personal protective equipment and proper ventilation are necessary when handling the substance to minimize exposure risks.

The study and industrial use of fluorinated alkenes like 2-chloro-3,3,3-trifluoropropene continue to evolve with advances in material science and environmental regulations. Their role in the development of specialized materials and sustainable technologies highlights their importance in both chemical research and commercial applications.

References

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