Lidoflazine
[CAS# 3416-26-0]

Identification

• Classification: API >> Circulatory system medication >> Prevention and treatment of angina pectoris
• Name: Lidoflazine
• Synonyms: 2-[4-[4,4-Bis(4-Fluorophenyl)Butyl]-1-Piperazinyl]-N-(2,6-Dimethylphenyl)Acetamide; 2-[4-[4,4-Bis(4-Fluorophenyl)Butyl]Piperazin-1-Yl]-N-(2,6-Dimethylphenyl)Ethanamide; Prestwick1_000381
• Molecular Formula: C₃₀H₃₅F₂N₃O
• Molecular Weight: 491.62
• CAS Registry Number: 3416-26-0
• EINECS: 222-312-8
• SMILES: C4=C(C(C1=CC=C(F)C=C1)CCCN3CCN(CC(NC2=C(C=CC=C2C)C)=O)CC3)C=CC(=C4)F
• InChI: 1S/C30H35F2N3O/c1-22-5-3-6-23(2)30(22)33-29(36)21-35-19-17-34(18-20-35)16-4-7-28(24-8-12-26(31)13-9-24)25-10-14-27(32)15-11-25/h3,5-6,8-15,28H,4,7,16-21H2,1-2H3,(H,33,36)
• InChIKey: ZBIAKUMOEKILTF-UHFFFAOYSA-N

Properties

• Density: 1.2±0.1g/cm³ (Cal.)
• Boiling point: 632.6±55.0°C at 760 mmHg (Cal.)
• Flash point: 336.4±31.5°C (Cal.)

References

• (1): Sean Ekins, Konstantin V. Balakin, Nikolay Savchuk, and Yan Ivanenkov. Insights for Human Ether-a-Go-Go-Related Gene Potassium Channel Inhibition Using Recursive Partitioning and Kohonen and Sammon Mapping Techniques, J. Med. Chem. 2006, 49(17), 5059-5071.