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L-Theanine
[CAS# 34271-54-0]

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Identification
ClassificationBiochemical >> Common amino acids and protein drugs
NameL-Theanine
SynonymsN-Ethyl-L-glutamine; 2-Amino-4-(ethylcarbamoyl)butanoic acid
Molecular StructureCAS # 34271-54-0, L-Theanine
Molecular FormulaC7H14N2O3
Molecular Weight174.20
Protein SequenceX
CAS Registry Number34271-54-0
SMILESCCNC(=O)CCC(C(=O)O)N
Properties
Melting point217-218 °C
Safety Data
Hazard Symbolssymbol   GHS07 Warning  Details
Risk Statements H315-H319-H335-H317  Details
Safety StatementsP261-P264-P271-P272-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501  Details
SDSAvailable
up Discovery and Applications
L-Theanine, an amino acid found primarily in tea leaves, was first discovered in 1949 by Japanese scientists. It is naturally occurring in Camellia sinensis, the plant species from which green, black, and white teas are derived. The compound gained attention for its relaxing and mood-enhancing properties. It is believed to act on the brain by increasing levels of neurotransmitters such as dopamine and serotonin, leading to a calming effect without causing drowsiness. The discovery of L-Theanine marked a significant milestone in understanding the bioactive components of tea and their potential health benefits.

L-Theanine is widely used as a natural supplement to reduce stress and promote relaxation. Studies have shown that it can help lower heart rate and blood pressure, as well as reduce subjective feelings of stress and anxiety. Its calming effects make it a popular choice for individuals seeking relief from the pressures of daily life or support during stressful situations.

Research suggests that L-Theanine may have cognitive-enhancing effects, improving attention, focus, and mental clarity. It is often combined with caffeine to mitigate the jittery effects of caffeine while still providing a boost in alertness and cognitive function. This combination is particularly popular in nootropic supplements aimed at enhancing cognitive performance and productivity.

L-Theanine has been studied for its potential role in improving sleep quality. It may help promote relaxation and reduce nighttime wakefulness, leading to better sleep outcomes. Some individuals find that L-Theanine supplementation before bedtime helps them fall asleep faster and experience deeper, more restful sleep.

L-Theanine is known for its mood-enhancing properties, promoting a sense of calmness and well-being. It may help alleviate symptoms of depression and anxiety by modulating neurotransmitter levels in the brain. Its gentle, non-sedating effects make it a preferred option for individuals seeking natural mood support.

Some studies suggest that L-Theanine may aid in weight management by promoting feelings of satiety and reducing cravings for high-calorie foods. By supporting stress reduction and mood enhancement, it may also help prevent emotional eating and promote healthier eating habits.

Research indicates that L-Theanine may have beneficial effects on cardiovascular health. It has been associated with improvements in lipid profiles, blood pressure regulation, and endothelial function, potentially reducing the risk of cardiovascular diseases such as hypertension and heart disease.

References

2023. L-Theanine: An update on its extraction, health benefits, and applications. Food Chemistry, 374.
DOI: 10.1016/j.foodchem.2022.104123
Market Analysis Reports
List of Reports Available for L-Theanine
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