5-Bromo-2-chloronicotinonitrile
[CAS# 405224-23-9]

Identification

• Classification: Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Pyridine compound >> Pyridine derivative
• Name: 5-Bromo-2-chloronicotinonitrile
• Synonyms: 5-Bromo-2-chloropyridine-3-carbonitrile
• Molecular Formula: C₆H₂BrClN₂
• Molecular Weight: 217.45
• CAS Registry Number: 405224-23-9
• EC Number: 688-427-4
• SMILES: C1=C(C=NC(=C1C#N)Cl)Br

Properties

• Solubility: 472.8 mg/L (25 °C water)
• Density: 1.9±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.629, Calc.^*
• Melting point: 76.65 °C
• Boiling Point: 272.7±35.0 °C (760 mmHg), Calc.^*, 277.24 °C
• Flash Point: 118.7±25.9 °C, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS05;GHS06;GHS07 Danger
• Risk Statements: H301-H315-H318-H335
• Safety Statements: P261-P264-P264+P265-P270-P271-P280-P301+P316-P302+P352-P304+P340-P305+P354+P338-P317-P319-P321-P330-P332+P317-P362+P364-P403+P233-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Skin irritation	Skin Irrit.	2	H315
Acute toxicity	Acute Tox.	3	H301
Specific target organ toxicity - single exposure	STOT SE	3	H335
Serious eye damage	Eye Dam.	1	H318
Eye irritation	Eye Irrit.	2	H319
Acute toxicity	Acute Tox.	3	H331
Acute toxicity	Acute Tox.	4	H332
Acute toxicity	Acute Tox.	4	H312
Acute toxicity	Acute Tox.	4	H302
Acute toxicity	Acute Tox.	3	H311