Pro-xylane
[CAS# 439685-79-7]

Identification

• Name: Pro-xylane
• Synonyms: (2S,3R,4S,5R)-2-(2-hydroxypropyl)oxane-3,4,5-triol
• Molecular Formula: C₈H₁₆O₅
• Molecular Weight: 192.21
• CAS Registry Number: 439685-79-7
• SMILES: CC(C[C@H]1[C@@H]([C@H]([C@@H](CO1)O)O)O)O

Properties

• Solubility: 1 mg/L (25 °C water)
• Density: 1.4±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.552, Calc.^*
• Melting point: 115.21 °C
• Boiling Point: 356.80 °C, 376.0±42.0 °C (760 mmHg), Calc.^*
• Flash Point: 181.2±27.9 °C, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H315-H319-H335-H303
• Safety Statements: P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501

Discovery and Applications

The discovery of Pro-xylane represents a groundbreaking advancement in the field of skincare and anti-aging technology. Derived from xylose, a natural sugar molecule found abundantly in plants, Pro-xylane is a key component capable of stimulating the synthesis of essential skin matrix molecules such as collagen and hyaluronic acid, thereby rejuvenating and replenishing the skin from within. Pro-xylane's unique molecular structure allows it to penetrate deep into the skin's layers, where it exerts its transformative effects on cellular function and matrix production.

Pro-xylane is widely utilized in anti-aging skincare formulations, including serums, creams, and masks. By stimulating collagen production and preserving skin matrix integrity, Pro-xylane helps minimize the appearance of fine lines, wrinkles, and sagging skin. In aesthetic medicine, Pro-xylane is incorporated into dermal filler formulations to augment facial volume and contour. Pro-xylane-based products are effective in addressing specific signs of aging, such as deep wrinkles and expression lines. Pro-xylane's ability to enhance skin hydration makes it a valuable ingredient in moisturizing formulations. By replenishing the skin's moisture barrier and retaining water molecules within the epidermis, Pro-xylane restores optimal hydration levels, resulting in softer, smoother, and more supple skin. Pro-xylane is often incorporated into sunscreen formulations to provide comprehensive anti-aging benefits. By reinforcing the skin's natural defense mechanisms and counteracting UV-induced damage, Pro-xylane helps prevent premature aging and photoaging.

References

2009. Synthesis of Pro-XylaneTM: A new biologically active C-glycoside in aqueous media. Bioorganic & Medicinal Chemistry Letters, 19(3).
DOI: 10.1016/j.bmcl.2008.12.037

2024. Holistic investigation of the anti‐wrinkle and repair efficacy of a facial cream enriched with C‐xyloside. Journal of Cosmetic Dermatology, 23(11).
DOI: 10.1111/jocd.16489