Hydrocortisone
[CAS# 50-23-7]

Identification

• Classification: API >> Hormone and endocrine-regulating drugs >> Adrenal corticosteroids
• Name: Hydrocortisone
• Synonyms: Cortisol; 11-beta,17-alpha,21-trihydroxypregn-4-ene-3,20-dione; Hydrocortisone Base
• Molecular Formula: C₂₁H₃₀O₅
• Molecular Weight: 362.46
• CAS Registry Number: 50-23-7
• EC Number: 200-020-1

Properties

• Melting point: 213-220 °C
• alpha: 166 ° (c=1, C2H5OH 25 °C)
• Decomposition: 220 °C

Safety Data

• Hazard Symbols: Xn
• Risk Statements: R62;R63
• Safety Statements: S36/37;S45

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Reproductive toxicity	Repr.	2	H361
Specific target organ toxicity - repeated exposure	STOT RE	2	H373
Reproductive toxicity	Repr.	1A	H360
Reproductive toxicity	Repr.	1B	H360
Reproductive toxicity	Repr.	1A	H360Df
Acute toxicity	Acute Tox.	3	H312
Reproductive toxicity	Repr.	2	H360
Acute toxicity	Acute Tox.	3	H302
Reproductive toxicity	Lact.	-	H362
Acute toxicity	Acute Tox.	3	H332
Skin irritation	Skin Irrit.	2	H315
Eye irritation	Eye Irrit.	2	H319
Acute toxicity	Acute Tox.	4	H312
Reproductive toxicity	Repr.	1B	H360Df
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412
Acute toxicity	Acute Tox.	4	H332
Acute toxicity	Acute Tox.	4	H302
Specific target organ toxicity - single exposure	STOT SE	3	H335