Phenylbutazone
[CAS# 50-33-9]

Identification

• Classification: API >> Antipyretic analgesics >> Non-steroidal anti-inflammatory drugs
• Name: Phenylbutazone
• Synonyms: 4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione; 1,2-Diphenyl-3,5-dioxo-4-n-butylpyrazoline
• Molecular Formula: C₁₉H₂₀N₂O₂
• Molecular Weight: 308.38
• CAS Registry Number: 50-33-9 (4297-92-1)
• EC Number: 200-029-0

Properties

• Melting point: 104-107 °C
• Water solubility: <0.1 g/100 mL at 23.5 °C

Safety Data

• Hazard Symbols: T;Xn
• Risk Statements: R45;R20/21/22;R36/37/38;R42/43
• Safety Statements: S53;S22;S26;S36/37/39;S45

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2	H319
Acute toxicity	Acute Tox.	3	H301
Specific target organ toxicity - single exposure	STOT SE	3	H335
Skin irritation	Skin Irrit.	2	H315
Acute toxicity	Acute Tox.	4	H332
Acute toxicity	Acute Tox.	4	H312
Carcinogenicity	Carc.	2	H351
Skin sensitization	Skin Sens.	1	H317
Respiratory sensitization	Resp. Sens.	1	H334
Reproductive toxicity	Repr.	2	H361
Acute toxicity	Acute Tox.	4	H302
Reproductive toxicity	Repr.	1B	H360
Specific target organ toxicity - repeated exposure	STOT RE	2	H373
Carcinogenicity	Carc.	1B	H350
Eye irritation	Eye Irrit.	2A	H319
Reproductive toxicity	Lact.	-	H362