L-Arginine 2-oxopentanedioate
[CAS# 5256-76-8]

Identification

• Classification: Biochemical >> Amino acids and their derivatives >> Arginine derivatives
• Name: L-Arginine 2-oxopentanedioate
• Synonyms: L-Arginine alpha-ketoglutarate (2:1)
• Molecular Formula: 2(C₆H₁₄N₄O₂).C₅H₆O₅
• Molecular Weight: 530.50
• CAS Registry Number: 5256-76-8
• EC Number: 226-059-4
• SMILES: C(C[C@@H](C(=O)O)N)CN=C(N)N.C(C[C@@H](C(=O)O)N)CN=C(N)N.C(CC(=O)O)C(=O)C(=O)O

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H315-H319-H335
• Safety Statements: P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Specific target organ toxicity - single exposure	STOT SE	3	H335
Skin irritation	Skin Irrit.	2	H315
Eye irritation	Eye Irrit.	2	H319

Discovery and Applications

L-Arginine 2-oxopentanedioate is a chemical compound that plays an important role in various biochemical processes and has found applications in medicinal and agricultural fields. It is a derivative of the amino acid L-arginine, which is crucial in the synthesis of proteins, and 2-oxopentanedioate, a compound involved in metabolic pathways. The combination of these two components results in a substance with specific properties and potential applications.

The discovery of L-Arginine 2-oxopentanedioate can be linked to the ongoing efforts in the early 21st century to explore new bioactive compounds that could have therapeutic potential. Research in metabolic pathways and amino acid derivatives revealed that conjugating L-arginine with 2-oxopentanedioate could yield compounds that affect nitrogen metabolism, oxidative stress, and other cellular functions. Such compounds have been explored for their ability to interact with enzymes and receptors involved in various physiological processes.

L-Arginine, as a precursor to nitric oxide, plays a vital role in vasodilation and blood circulation. When combined with 2-oxopentanedioate, the resulting compound exhibits enhanced activity that has implications for conditions related to cardiovascular health. The interaction between L-Arginine 2-oxopentanedioate and metabolic pathways suggests it may be a potential candidate for drug development aimed at improving vascular function or mitigating conditions like hypertension. The specific metabolic effects of the compound could be explored further to understand its potential therapeutic benefits in managing oxidative stress or modulating nitric oxide synthesis.

Another area of application for L-Arginine 2-oxopentanedioate is in the field of agriculture. Some studies suggest that compounds like L-Arginine 2-oxopentanedioate may have benefits in plant growth, particularly in enhancing stress resistance or boosting the growth of plants under suboptimal conditions. The role of amino acid derivatives in plant metabolism is an area of active research, with many such compounds potentially serving as biostimulants or growth enhancers. These compounds can also help plants cope with abiotic stresses like drought or salinity, thus improving crop yields in challenging environments.

In addition, L-Arginine 2-oxopentanedioate holds promise for industrial applications in the development of biomaterials. The combination of amino acids and organic acids can lead to the synthesis of polymers or composite materials that are biodegradable and possess specific mechanical or chemical properties. These materials may find uses in medical devices, drug delivery systems, or as biodegradable plastics, contributing to more sustainable practices in the industrial sector.

In conclusion, L-Arginine 2-oxopentanedioate is a compound that bridges amino acid metabolism and organic acid pathways, showing promise in various therapeutic, agricultural, and industrial applications. Its potential in improving cardiovascular health, aiding plant growth, and contributing to the development of sustainable materials makes it an interesting area for future research and practical applications.

References

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