Amitriptyline hydrochloride
[CAS# 549-18-8]

Identification

• Classification: API >> Nervous system medication >> Antidepressant, manic
• Name: Amitriptyline hydrochloride
• Synonyms: 3-(10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride
• Molecular Formula: C₂₀H₂₃N.HCl
• Molecular Weight: 313.87
• CAS Registry Number: 549-18-8
• EC Number: 208-964-6

Properties

• Melting point: 196-197 °C

Safety Data

• Hazard Symbols: T
• Risk Statements: R23/24/25;R36/37/38;R42/43;R63
• Safety Statements: S22;S26;S36/37/39;S45

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400
Chronic hazardous to the aquatic environment	Aquatic Chronic	1	H410
Acute toxicity	Acute Tox.	3	H301
Specific target organ toxicity - single exposure	STOT SE	1	H370
Eye irritation	Eye Irrit.	2	H319
Acute toxicity	Acute Tox.	4	H302
Serious eye damage	Eye Dam.	1	H318
Reproductive toxicity	Lact.	-	H362
Reproductive toxicity	Repr.	2	H361
Reproductive toxicity	Repr.	2	H361d
Acute toxicity	Acute Tox.	3	H311
Skin irritation	Skin Irrit.	2	H315
Skin sensitization	Skin Sens.	1	H317
Respiratory sensitization	Resp. Sens.	1	H334
Specific target organ toxicity - single exposure	STOT SE	3	H335
Acute toxicity	Acute Tox.	2	H330
Carcinogenicity	Carc.	1B	H350
Chronic hazardous to the aquatic environment	Aquatic Chronic	4	H413
Chronic hazardous to the aquatic environment	Aquatic Chronic	2	H411
Acute toxicity	Acute Tox.	3	H331

• Transport Information: UN 2811