2-Amino-1-(2,5-dimethoxyphenyl)ethanone hydrochloride
[CAS# 671224-08-1]

Identification

• Classification: Organic raw materials >> Ketone compound
• Name: 2-Amino-1-(2,5-dimethoxyphenyl)ethanone hydrochloride
• Molecular Formula: C₁₀H₁₃NO₃.HCl
• Molecular Weight: 231.68
• Protein Sequence: G
• CAS Registry Number: 671224-08-1
• EC Number: 813-607-8
• SMILES: COC1=CC(=C(C=C1)OC)C(=O)CN.Cl

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H302
• Safety Statements: P264-P270-P301+P317-P330-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	4	H302

Discovery and Applications

2-Amino-1-(2,5-dimethoxyphenyl)ethanone hydrochloride is an organic compound primarily of interest in pharmaceutical and biochemical research. It features an ethanone (acetyl) group attached to an amino group, along with a phenyl ring that is substituted by two methoxy groups in the 2- and 5-positions. The hydrochloride salt form enhances its solubility and stability, making it easier to handle in laboratory settings.

The discovery of 2-Amino-1-(2,5-dimethoxyphenyl)ethanone hydrochloride is linked to investigations into the structure-activity relationships of various substituted aromatic compounds. Such molecules are known for their potential in modulating biological activities, particularly due to the presence of electron-donating methoxy groups on the aromatic ring. The compound’s structural characteristics suggest its possible involvement in pathways of neurotransmitter synthesis, and it has drawn attention for its potential applications in neurochemical studies.

One significant application of 2-Amino-1-(2,5-dimethoxyphenyl)ethanone hydrochloride is its use as an intermediate in the synthesis of pharmacologically active compounds. Researchers are interested in its role in the development of analogs that target specific neurological receptors, which could be useful in the treatment of conditions such as depression, anxiety, and other mood disorders. The presence of the amino group adjacent to the acetyl group in this compound opens pathways for further chemical modifications, enabling the design of molecules with enhanced therapeutic properties.

In addition, 2-Amino-1-(2,5-dimethoxyphenyl)ethanone hydrochloride is valuable in medicinal chemistry for probing the effects of methoxy substitutions on the pharmacokinetics and pharmacodynamics of related compounds. The methoxy groups can influence the molecule’s lipophilicity and electronic properties, which in turn can affect its interaction with biological targets. Researchers use this compound to explore these relationships, aiding the design of more effective drugs with fewer side effects.

Beyond pharmaceuticals, the compound has potential applications in organic synthesis. It can serve as a building block in the production of more complex molecules, including those used in the study of enzyme inhibitors or in the development of materials with specific electronic properties. The versatility of this compound in both biological and synthetic chemistry highlights its importance as a chemical tool in various research fields.

In summary, 2-Amino-1-(2,5-dimethoxyphenyl)ethanone hydrochloride is a compound of considerable interest for its potential applications in drug development, neurochemical research, and organic synthesis. As investigations into its properties continue, it may contribute to advancements in both therapeutic and industrial chemistry.

References

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