5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
[CAS# 720720-96-7]

Identification

• Classification: Organic raw materials >> Carboxylic compounds and derivatives
• Name: 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
• Synonyms: 5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxylic acid;hydrochloride
• Molecular Formula: C₈H₁₀N₂O₂S.HCl
• Molecular Weight: 234.70
• CAS Registry Number: 720720-96-7
• EC Number: 858-363-3
• SMILES: CN1CCC2=C(C1)SC(=N2)C(=O)O.Cl

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H302-H315-H319-H335
• Safety Statements: P261-P264-P264+P265-P270-P271-P280-P301+P317-P302+P352-P304+P340-P305+P351+P338-P319-P321-P330-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2A	H319
Skin irritation	Skin Irrit.	2	H315
Specific target organ toxicity - single exposure	STOT SE	3	H335
Acute toxicity	Acute Tox.	4	H302

Discovery and Applications

5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride is a chemical compound that belongs to the class of thiazolo-pyridine derivatives. These types of compounds have attracted significant interest in the field of medicinal chemistry due to their diverse biological activities. The structure of this compound consists of a fused thiazole and pyridine ring system, with a carboxylic acid group at the 2-position of the pyridine ring. The methyl group at the 5-position of the thiazole ring adds to the molecule's uniqueness and reactivity.

The discovery of 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride was a result of efforts to explore thiazole and pyridine-containing compounds for their potential therapeutic properties. Compounds containing both thiazole and pyridine rings are known for their ability to interact with biological targets, including enzymes, receptors, and ion channels. These compounds often display a wide range of biological effects, making them valuable candidates for drug development.

One of the primary applications of 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride is in the development of novel therapeutic agents. Due to the presence of both thiazole and pyridine moieties, this compound has shown promise as an inhibitor of various enzymes and receptors involved in diseases such as cancer, inflammation, and neurodegenerative disorders. The carboxylic acid group in the compound provides a functional handle that can be further modified to enhance its pharmacological activity or selectivity. Researchers have synthesized derivatives of this compound in efforts to improve its potency and bioavailability for use in clinical settings.

In addition to its potential as a therapeutic agent, 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride has also been studied for its potential role in the development of bioactive materials. Its ability to form stable complexes with metal ions makes it a candidate for use in the design of coordination compounds and catalysts for organic reactions. The compound's ability to bind to metal centers could lead to its application in fields such as materials science, where such metal-ligand complexes are used in the synthesis of functionalized materials and catalysts for chemical processes.

Furthermore, this compound has been explored in the area of agricultural chemistry. Thiazole and pyridine-based compounds are known to exhibit pesticidal and herbicidal activities, making 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride a potential candidate for the development of new agrochemicals. These compounds can act as plant growth regulators or pest control agents, influencing key biological processes in plants or pests. The biological activity of the compound can be modulated by modifying the structure at key positions, including the carboxylic acid group.

References

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