Glyoxal
CAS 107-22-2
Glyoxal is the smallest dialdehyde, yet two reactive carbonyl groups give it an outsized role in crosslinking paper, textiles, and polymers.
Glyoxal (CAS 107-22-2) shows how molecular structure determines chemical role. Glyoxal (CAS 107-22-2) is ethanedial, OHC-CHO, the smallest molecule containing two aldehyde groups. That apparent simplicity produces unusually rich chemistry because both carbonyl carbons are electrophilic and can react with compounds containing amino or hydroxyl groups. PubChem and industrial sources describe glyoxal as a major crosslinking and intermediate chemical used in paper, textiles, polymers, leather, adhesives, and organic synthesis. Crosslinking can improve wet strength in paper or alter wrinkle resistance and dimensional stability in textile systems. Glyoxal is commonly supplied as an aqueous solution because the free dialdehyde is highly reactive and participates in hydration and oligomerization equilibria. It is also a useful heterocycle precursor, including reactions that build nitrogen-containing rings such as imidazole derivatives.
Published:
2026-10-01