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2-Bromo-5-chlorophenol

CAS 13659-23-9

2-Bromo-5-chlorophenol
Bromine and chlorine sit next to the same benzene ring. Surely they're basically doing the same job?
Not quite. 2-Bromo-5-chlorophenol is a nice example of something synthetic chemists love: molecular parts that look similar but can behave differently. The molecule has three useful features: An -OH group. A bromine atom. A chlorine atom.

The -OH can be used to attach another molecular fragment through oxygen. The bromine can act as another connection point. With modern cross-coupling chemistry, chemists can replace it with a new piece of molecular architecture. And the chlorine?
Published: 2026-08-16
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