O,O-Dimethyl phosphoramidothioate
CAS 17321-47-0
Organophosphorus pesticide chemistry showed how a few substitutions around one phosphorus atom can dramatically change both usefulness and danger.
O,O-Dimethyl phosphoramidothioate belongs to the organophosphorus chemistry historically explored for pesticide activity. Around one phosphorus center, sulfur, amino, and methoxy substituents create a highly tunable scaffold. Small structural changes can greatly alter biological activity, persistence, and toxicity. The class became both a powerful source of insecticides and a major lesson in why activity optimization cannot be separated from toxicology.
Published:
2026-09-10
