Tigecycline
CAS 220620-09-7
A next-generation antibiotic does not always need a new target. Tigecycline shows how redesigning an old scaffold can address resistance.
Tigecycline (CAS 220620-09-7) is 9-t-butylglycylamido-minocycline. One strategically placed side chain helped an established antibiotic scaffold evade major efflux and ribosomal-protection resistance mechanisms.
Published:
2026-09-18
