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Chloromethyl methyl sulfide

CAS 2373-51-5

Chloromethyl methyl sulfide
Sometimes chemists deliberately add a group to a molecule...
just so they can remove it later. That isn't wasted chemistry. It's protection. Chloromethyl methyl sulfide is a tiny two-carbon reagent used to install the methylthiomethyl, or MTM, protecting group. Suppose a molecule contains an alcohol.

The -OH group is useful—but perhaps not yet. During the next few synthetic steps, it might react when the chemist wants something else to react instead. So the hydroxyl group gets a temporary molecular cover: -OH becomes -O-CH2-S-CH3.
Published: 2026-08-16
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