Global Chemical Database

Methyl 4-(piperidin-4-yl)benzoate

CAS 281235-04-9

Methyl 4-(piperidin-4-yl)benzoate
A piperidine ring and a transformable aromatic ester make CAS 281235-04-9 a flexible scaffold for medicinal-chemistry synthesis.
Methyl 4-(piperidin-4-yl)benzoate (CAS 281235-04-9) illustrates how molecular structure determines chemical role. Methyl 4-(piperidin-4-yl)benzoate (CAS 281235-04-9) combines a piperidine ring with a para-substituted methyl benzoate. Both motifs are common in medicinal chemistry: piperidine provides a basic, three-dimensional nitrogen-containing ring that can be further substituted, while the aromatic ester offers a rigid linker and a functional group that can be hydrolyzed or transformed into amides and other derivatives. The carbon-carbon bond connecting the piperidine 4-position to the para position of the benzene ring creates a useful scaffold for building larger molecules without placing the ring nitrogen directly next to the aromatic system. Public exact-CAS information is largely catalog and synthesis based, so the compound should be treated as a pharmaceutical/research intermediate rather than assigned an unsupported biological target.
Published: 2026-10-01
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