3-Ethynyl-1-azetidinecarboxylic acid tert-butyl ester

CAS 287193-01-5

tert-Butyl 3-ethynylazetidine-1-carboxylate combines a saturated nitrogen ring with two useful synthetic features: a terminal alkyne and a Boc-protected nitrogen. CAS 287193-01-5 identifies this particular building block. A patent titled Radiolabeled compounds explicitly uses it in couplings with aromatic bromides, providing a documented role in carbon-carbon bond construction. The starting reagent is not thereby radioactive, nor does it automatically share the properties of later products. Its structure illustrates staged synthesis: the alkyne extends the carbon framework while the nitrogen remains temporarily protected. Reading the name carefully also matters, because the Boc carbamate is attached through nitrogen rather than being a free carboxylic acid on the ring. The verified application is a precise example of molecular construction from a compact, preassembled framework.