Global Chemical Database

2'-Amino-5'-hydroxypropiophenone

CAS 35364-15-9

2'-Amino-5'-hydroxypropiophenone
Small synthetic intermediates can sit quietly behind the construction of medicinal chemistry's most elaborate ring systems.
2'-Amino-5'-hydroxypropiophenone (CAS 35364-15-9) has a chemical story that connects molecular identity with practical chemistry. 2'-Amino-5'-hydroxypropiophenone, systematically 1-(2-amino-5-hydroxyphenyl)propan-1-one, is a compact aromatic ketone whose amino, phenolic hydroxyl and ketone functions make it a densely functionalized building block. Specialist synthesis and reference-material sources connect it with intermediates used in irinotecan and other camptothecin-related chemistry. It is not itself an anticancer medicine. Instead, its functional-group arrangement gives chemists entry points for constructing more elaborate fused-ring structures and controlling downstream transformations. It is also encountered as an irinotecan-related impurity or reference material, linking process chemistry with analytical quality control.

The exact CAS identity matters because related salts, stereoisomers, intermediates and finished medicines can play very different roles even when their names look closely related.

Its story also shows why synthesis and analytical control belong together: chemists must create the intended structure, distinguish it from process-related species and verify the form actually being handled.
Published: 2026-09-21
View complete chemical information for 2'-Amino-5'-hydroxypropiophenone