5-Bromopyrimidine

CAS 4595-59-9

5-Bromopyrimidine provides a defined address for further synthesis. CAS 4595-59-9 combines a pyrimidine ring with bromine at carbon 5, marking a documented site for carbon-carbon bond construction. An independently checked nickel-catalyzed Suzuki-Miyaura procedure uses it to prepare a furanyl-substituted pyrimidine. Other research combines coupling with modification at another ring position to build more elaborate substitution patterns. These examples demonstrate actual synthetic roles while leaving the properties of final derivatives to separate investigation. The two ring nitrogens and the bromine position both matter, so the molecule should not be treated as interchangeable with every aromatic bromide. Its story shows how precise connectivity turns a small heterocycle into a controlled starting point for a wider family of molecules in planned synthetic research.