Ethyl 3-(N,N-dimethylamino)acrylate
CAS 924-99-2
An enamine donor and ester acceptor create a push-pull alkene whose polarized carbon atoms are useful for selective bond construction.
Ethyl 3-(N,N-dimethylamino)acrylate (CAS 924-99-2) illustrates how molecular structure determines chemical role. Ethyl 3-(N,N-dimethylamino)acrylate is an enamine ester in which an electron-rich dimethylamino group is conjugated through a carbon-carbon double bond with an electron-withdrawing ethyl ester. This push-pull arrangement makes the molecule useful for constructing heterocycles and functionalized unsaturated compounds. The dimethylamino group can act as an activating substituent and, in suitable reactions, as a leaving group, while the ester remains available for hydrolysis, amidation, reduction, and other transformations. Enamino esters are valuable because their carbon atoms are electronically differentiated, allowing regioselective bond formation with nucleophiles or electrophiles. Public exact-CAS information is principally synthetic, so this substance is best described as an organic and medicinal-chemistry intermediate rather than an active drug.
Published:
2026-10-01