Global Chemical Database

3-Nitrobenzotrifluoride

CAS 98-46-4

3-Nitrobenzotrifluoride
Can electricity replace a bottle of reducing agent? 3-Nitrobenzotrifluoride offers a fascinating real-world example.
The molecule carries two very different groups: NO2 and CF3. Chemists often want to change one while keeping the other. Reduce NO2 and it becomes NH2. The CF3 group stays where it is.

That gives 3-(trifluoromethyl)aniline, a useful building block for pharmaceutical and agrochemical synthesis. Nitro-to-amine reduction is very old chemistry. But researchers recently gave it a modern twist. Instead of relying on a conventional reducing agent, they used electrochemistry.
Published: 2026-08-18
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