Tetrahexyldecyl ascorbate
[CAS# 183476-82-6]

Identification

• Name: Tetrahexyldecyl ascorbate
• Synonyms: BV-OSC; Nikkol VC-IP; VC-IP; Vitamin C tetra-isopalmitate; L-Ascorbic acid 2,3,5,6-tetrakis(2-hexyldecanoate)
• Molecular Formula: C₇₀H₁₂₈O₁₀
• Molecular Weight: 1129.76
• CAS Registry Number: 183476-82-6
• EC Number: 430-110-8
• SMILES: CCCCCCCCC(CCCCCC)C(=O)OC[C@@H]([C@@H]1C(=C(C(=O)O1)OC(=O)C(CCCCCC)CCCCCCCC)OC(=O)C(CCCCCC)CCCCCCCC)OC(=O)C(CCCCCC)CCCCCCCC

Properties

• Solubility: Insoluble (2.3E^-8 g/L) (25 ºC), Calc.^*
• Density: 0.98±0.1 g/cm³ (20 ºC 760 Torr), Calc.^*
• Index of Refraction: 1.491, Calc.^*
• Boiling Point: 947.6±64.0 ºC (760 mmHg), Calc.^*
• Flash Point: 333.6±34.0 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07;GHS09 Warning
• Hazard Statements: H317-H400-H410
• Precautionary Statements: P261-P272-P273-P280-P302+P352-P321-P333+P317-P362+P364-P391-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Chronic hazardous to the aquatic environment	Aquatic Chronic	1	H410
Skin sensitization	Skin Sens.	1	H317
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400
Chronic hazardous to the aquatic environment	Aquatic Chronic	4	H413

Discovory and Applicatios

Tetrahexyldecyl ascorbate, a lipid-soluble derivative of vitamin C, emerged as a remarkable discovery in the realm of skincare and cosmetic science. Its development stemmed from efforts to overcome the limitations of traditional water-soluble forms of vitamin C, such as ascorbic acid, which are susceptible to oxidation and may cause irritation in sensitive skin. Tetrahexyldecyl ascorbate was synthesized through chemical modifications to enhance its stability, bioavailability, and compatibility with the skin, leading to its recognition as a highly effective and well-tolerated alternative to traditional vitamin C formulations.

Tetrahexyldecyl ascorbate serves as a potent antioxidant in skincare formulations, helping neutralize free radicals generated by environmental stressors such as UV radiation, pollution, and oxidative stress. Its antioxidant properties protect the skin from premature aging, oxidative damage, and collagen degradation, preserving skin elasticity and firmness. Tetrahexyldecyl ascorbate promotes skin brightening and even complexion by inhibiting melanin synthesis and reducing hyperpigmentation. Tetrahexyldecyl ascorbate stimulates collagen synthesis in the skin, promoting firmness, elasticity, and resilience. By enhancing collagen production, Tetrahexyldecyl ascorbate helps minimize the appearance of fine lines, wrinkles, and sagging skin. Tetrahexyldecyl ascorbate offers comprehensive anti-aging benefits by addressing multiple signs of aging, including wrinkles, fine lines, loss of elasticity, and uneven skin tone. Tetrahexyldecyl ascorbate helps repair and prevent sun damage by reducing UV-induced inflammation, oxidative stress, and DNA damage in the skin. Its anti-inflammatory properties alleviate sunburn and sun-induced redness, while its antioxidant effects neutralize free radicals generated by UV exposure, minimizing photoaging and photodamage. Tetrahexyldecyl ascorbate enhances skin hydration and strengthens the skin's natural barrier function by promoting lipid synthesis and preventing transepidermal water loss. Tetrahexyldecyl ascorbate exhibits anti-inflammatory properties that help reduce inflammation and redness associated with acne and blemishes.