2-Octyl-1-dodecanol
[CAS# 5333-42-6]

Identification

• Classification: Analytical chemistry >> Analytical reagent >> Ion chromatography reagent
• Name: 2-Octyl-1-dodecanol
• Synonyms: (2R)-2-Octyl-1-dodecanol
• Molecular Formula: C₂₀H₄₂O
• Molecular Weight: 298.55
• CAS Registry Number: 5333-42-6
• EC Number: 226-242-9
• SMILES: CCCCCCCCCCC(CCCCCCCC)CO

Properties

• Density: 0.8±0.1 g/cm³, Calc.^*
• Melting point: 1 ºC
• Index of Refraction: 1.452, Calc.^*
• Boiling Point: 357.7±10.0 ºC (760 mmHg), Calc.^*
• Flash Point: 129.7±7.1 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H315-H319-H335
• Precautionary Statements: P261-P305+P351+P338

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2	H319
Skin irritation	Skin Irrit.	2	H315
Specific target organ toxicity - single exposure	STOT SE	3	H335

Discovory and Applicatios

2-Octyl-1-dodecanol is an organic compound classified as a fatty alcohol, primarily used in various industrial applications, including as an emulsifier, lubricant, and surfactant. It is a long-chain alcohol with a molecular structure comprising a dodecyl group (12 carbon atoms) and an octyl group (8 carbon atoms), both of which are alkyl chains. This structure makes 2-octyl-1-dodecanol hydrophobic, allowing it to interact with both lipophilic and hydrophilic substances, which enhances its utility in a wide range of formulations.

The discovery of 2-octyl-1-dodecanol can be traced to the broader development of fatty alcohols, which are typically derived from natural sources such as vegetable oils or petrochemical processes. Fatty alcohols, including 2-octyl-1-dodecanol, have been known for their use in the production of detergents, personal care products, and industrial applications due to their emulsifying properties. As researchers and manufacturers began exploring compounds with longer alkyl chains, it became clear that 2-octyl-1-dodecanol possessed desirable characteristics that made it suitable for a variety of formulations.

2-Octyl-1-dodecanol is widely used in the cosmetic and personal care industries as an emulsifier and skin-conditioning agent. Its ability to stabilize emulsions makes it an ideal component in lotions, creams, and other skin-care products, where it helps blend oils and water-based ingredients. The compound is also known for its emollient properties, which allow it to improve the texture and smoothness of the skin, providing a soft, hydrated feel. In this application, 2-octyl-1-dodecanol acts as a mild solvent that aids in the dispersion of other ingredients, such as active substances and fragrances, ensuring a uniform and aesthetically pleasing product.

In addition to its use in cosmetics, 2-octyl-1-dodecanol is employed in the formulation of industrial products. It serves as a lubricant, particularly in applications where metalworking or other friction-reducing processes are required. Its hydrophobic nature helps in reducing wear and tear between mechanical parts, providing long-lasting protection. Furthermore, it can be used as a surfactant in cleaning agents, where it assists in breaking down grease and oils.

The versatility of 2-octyl-1-dodecanol extends to its role in the formulation of various food-grade products and pharmaceuticals, where it may be used as a carrier or stabilizing agent for other components. Additionally, it is sometimes included in the production of household cleaning products and agricultural formulations, where it contributes to the overall efficiency and stability of the mixture.

While 2-octyl-1-dodecanol is generally regarded as safe for use in personal care products, as with any chemical, appropriate usage levels and safety standards are essential to avoid adverse effects. Regulatory bodies such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) provide guidelines for its safe use, particularly in cosmetics, to ensure consumer safety.

In conclusion, 2-octyl-1-dodecanol is a valuable compound with wide-ranging applications due to its emollient, emulsifying, and lubricating properties. Its discovery and continued use in both consumer and industrial products highlight its importance in modern formulations, particularly in the personal care, pharmaceutical, and industrial sectors.