1-[(2R,4S,5R)-4-羟基-5-(羟基甲基)四氢噻吩-2-基]-5-甲基嘧啶-2,4-二酮
[CAS# 134111-33-4]

基本信息

• 产品名称: 1-[(2R,4S,5R)-4-羟基-5-(羟基甲基)四氢噻吩-2-基]-5-甲基嘧啶-2,4-二酮
• 英文名: 1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Thiolan-2-Yl]-5-Methylpyrimidine-2,4-Dione
• 别名: 1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrothiophen-2-Yl]-5-Methyl-Pyrimidine-2,4-Dione; 1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)-2-Tetrahydrothiophenyl]-5-Methylpyrimidine-2,4-Dione; 1-[(2R,4S,5R)-4-Hydroxy-5-Methylol-Tetrahydrothiophen-2-Yl]-5-Methyl-Pyrimidine-2,4-Quinone
• 分子式: C₁₀H₁₄N₂O₄S
• 分子量: 258.29
• CAS 登录号: 134111-33-4
• 分子行输入简码 SMILES: [C@H]1(S[C@@H]([C@@H](O)C1)CO)N2C(=O)NC(=O)C(=C2)C
• 国际化学标识码 InChI: 1S/C10H14N2O4S/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
• 国际化学标识检索码 InChIKey: IVUDHNYLTWOARV-XLPZGREQSA-N

物理化学性质

• 密度: 1.474g/cm³ （计算值）

参考文献

• (1): Hiroko Koyama, Siqin, Zhouen Zhang, Kengo Sumi, Yuma Hatta, Hiroko Nagata, Hisashi Doi and Masaaki Suzuki. Highly efficient syntheses of [methyl-11C]thymidine and its analogue 4′-[methyl-11C]thiothymidine as nucleoside PET probes for cancer cell proliferation by Pd0-mediated rapid C-[C]methylation, Org. Biomol. Chem., 2011, 9, 4287.