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Home >> Categories of Chemicals >> Biochemical >>Inhibitor >>Protein tyrosine kinase

Category of Chemicals

Protein tyrosine kinase

Protein tyrosine kinases are involved in cell signaling, and their abnormal activity is linked to various cancers. Tyrosine kinase inhibitors, such as Imatinib, target these proteins, blocking signals that promote cancer cell growth. They've revolutionized cancer treatment, offering more targeted and less toxic therapies.

Products of Protein tyrosine kinase
CAS No.Product NameMolecular Formula
1001350-96-4BMS 754807C23H24FN9O
1001917-37-8MK-8033C25H21N5O3S
1002304-34-8AMG 208C22H17N5O2
1022150-57-7SGX 523C18H13N7S
1029712-80-82-Fluoro-N-methyl-4-[7-[(quinolin-6-yl)methyl]imidazo[1,2-b]-[1,2,4]triazin-2-yl]benzamideC23H17FN6O
1032900-25-6LDK 378C28H36ClN5O3S
1033769-28-6N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]-ureaC28H21F4N5O2
1037624-75-11-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N3-[(7S)-6,7,8,9-tetrahydro-7-(1-pyrrolidinyl)-5H-benzocyclohepten-2-yl]-1H-1,2,4-triazole-3,5-diamineC30H34N8
1050500-29-2N-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-propenamide 4-methylbenzenesulfonateC24H18ClFN4O2.C7H8O3S
1056634-68-4CYT 387C23H22N6O2
1058137-23-76-[[7-[(1-Aminocyclopropyl)methoxy]-6-methoxy-4-quinolinyl]oxy]-N-methyl-1-naphthalenecarboxamideC26H25N3O4
1061353-68-1PND 1186C25H26F3N5O3
1092364-38-91-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-oneC23H21Cl2FN4O3
1092499-93-8NVP-BSK 805C27H28F2N6O
1092788-83-4PP 121C17H17N7
1097917-15-1ASP 3026C29H40N8O3S
1100598-32-0EMD-1214063C29H28N6O2
1110813-31-4DacomitinibC24H25ClFN5O2
1116235-97-2GSK1838705AC27H29FN8O3
1140909-48-3Cabozantinib (S)-malateC28H24FN3O5.C4H6O5
1174046-72-0N-[4-((2-Amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl]-5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxamideC23H15ClF2N4O3
1185763-69-26-[[6-(1-Methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl]quinolineC20H16N6
1186206-79-0N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[[[5-(2-thienyl)-3-pyridinyl]carbonyl]amino]benzamideC32H32F3N5O2S
1197958-12-55-Chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamineC26H34ClN6O2P
1202757-89-8N-[3-[[5-Fluoro-2-[[4-(2-methoxyethoxy)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-2-propenamideC22H22FN5O3
1213269-23-8WZ 4002C25H27ClN6O3
1214265-56-1WZ 3146C24H25ClN6O2
1214265-57-2WZ 8040C24H25ClN6OS
1225278-16-9DCC-2618C26H21F2N5O3
1225451-84-26,7-Dimethoxy-4-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]quinazolineC13H12N4O2S2
1234480-84-2LRRK2-IN-1C31H38N8O3
1246525-60-9SR 1078C17H10F9NO2
1254473-64-74-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanolC21H19Cl2N5O2
1256580-46-7CH 5424802C30H34N4O2
1257628-77-54-Methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[2-(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamideC29H27F3N6O
1356962-20-3N-[4-(4-Amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)-2-pyrimidinamineC24H25ClN6O
1361030-48-9N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluoro-2-methylphenyl)-1H-pyrazole-3-carboxamideC30H26F2N4O5
1374640-70-6N-[3-[[2-[[4-(4-Acetyl-1-piperazinyl)-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamideC27H28F3N7O3
1375465-09-0N-[3-[[2-[[4-[[1-(2-Fluoroethyl)-3-azetidinyl]amino]-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamideC26H27F4N7O2
1421373-65-0N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamideC28H33N7O2
1431525-23-3N-[2-Methyl-5-[9-[4-[(methylsulfonyl)amino]phenyl]-2-oxobenzo[h]-1,6-naphthyridin-1(2H)-yl]phenyl]-2-propenamideC29H24N4O4S
1433953-83-3SAR131675C18H22N4O4
1454846-35-5PF 06463922C21H19FN6O2
146535-11-76,7-Dimethoxy-2-phenylquinoxalineC16H14N2O2
148741-30-4Tyrphostin AG 879C18H24N2OS
1493694-70-4trans-4-[[2-(Butylamino)-5-[5-(4-morpholinylmethyl)-2-pyridinyl]-4-pyrimidinyl]amino]cyclohexanolC24H36N6O2
1493764-08-12-(Butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-[[4-(1H-imidazol-1-yl)phenyl]methyl]-5-pyrimidinecarboxamideC25H33N7O2
153436-53-4AG 1478C16H14ClN3O2
183320-51-6OSI 420C21H21N3O4.HCl
183322-45-46,7-Dimethoxy-4-[N-(3-bromophenyl)amino]quinazoline hydrochlorideC16H14BrN3O2.HCl
1887015-55-55-Fluoro-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrileC7H5FN2O
189224-48-42-(2-Ethyl-2,3-dihydro-2-benzofuranyl)-1H-imidazoleC13H14N2O
193000-39-45-[(7-Benzyloxyquinazolin-4-yl)amino]-4-fluoro-2-methylphenol hydrochlorideC22H18FN3O2.HCl
194413-58-6SemaxanibC15H14N2O
194423-06-8N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-butynamideC18H13BrN4O
194423-15-9N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamideC17H13BrN4O
196868-63-0PQ 401C18H16ClN3O2
211555-05-4WHI-P 97C16H13Br2N3O3
212141-51-0Vatalanib dihydrochlorideC20H15ClN4.2(HCl)
219766-25-3N-[2-[[(Hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]benzo[b]thiophene-2-carboxamideC22H21N3O3S
228559-41-9KI 8751C24H18F3N3O4
252916-29-3TSU-68C18H18N2O3
257933-82-7PelitinibC24H23ClFN5O2
286370-15-8KRN 633C20H21ClN4O4
343787-29-1CP 673451C24H27N5O2
417716-92-84-[3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6-quinolinecarboxamideC21H19ClN4O4
468740-43-4BMS-536924C25H26ClN5O3
475108-18-0AV-951C22H19ClN4O5
475488-23-4ADW 742C28H31N5O
475489-16-8[7-[cis-3-[(Azetidin-1-yl)methyl]cyclobutyl]-5-(3-benzyloxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amineC27H29N5O
477575-56-7PHA 665752C32H34Cl2N4O4S
497839-62-06-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amineC27H32N6
50-57-7LypressinC46H65N13O12S2
504433-23-21,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-oneC17H13N3O
537705-08-1CP-724714C27H27N5O3
571190-30-2PalbociclibC24H29N7O2
610798-31-7IcotinibC22H21N3O4
635702-64-6Pazopanib hydrochlorideC21H23N7O2S.HCl
65678-07-12-[[3-Bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]propanedinitrileC14H13BrN2O
656820-32-5ReversineC21H27N7O
658084-23-2SU 11274C28H30ClN5O4S
670220-88-9CrenolanibC26H29N5O2
690206-97-4N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxy-4-quinazolinamineC16H13ClFN3O2
714971-09-2BMS 599626C27H27FN8O3
728033-96-3OSI 930C22H16F3N3O2S
761439-42-3NVP-TAE684C30H40ClN7O3S
790299-79-5MasitinibC28H30N6OS
796967-16-3LinifanibC21H18FN5O
811803-05-1N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamideC24H23N5O
845272-21-1ARRY 334543C22H19ClN6O2S
848942-61-0SapitinibC23H25ClFN5O3
849217-64-7ForetinibC34H34F2N4O6
849217-68-1CabozantinibC28H24FN3O5
850140-73-7Afatinib dimaleateC24H25ClFN5O3.2(C4H4O4)
850879-09-3MP 470C23H21N5O3S
857876-30-3Motesanib diphosphateC22H23N5O.2(H3PO4)
857890-39-2Lenvatinib mesylateC21H19ClN4O4.CH4O3S
867160-71-2OSI-906C26H23N5O
870483-87-75-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamineC20H22N4O3
871026-44-7TAK 285C26H25ClF3N5O3
875337-44-3MGCD-265C26H20FN5O2S2
883986-34-3AZD2932C24H25N5O4
905854-02-6TivantinibC23H19N3O2
913376-83-7AMG 458C30H29N5O5
917879-39-1N-[(2R)-1,4-Dioxan-2-ylmethyl]-N-methyl-N'-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfuric diamideC24H25N5O5S
928037-13-2E-7050C33H37F2N7O4
937265-83-3ARRY 380C29H27N7O4S
940310-85-0NVP-BHG 712C26H20F3N7O
943540-75-8JNJ 38877605C19H13F2N7
948557-43-54-(6-Methoxy-2-naphthyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazoleC26H21N3O2S
953769-46-5BLZ 945C20H22N4O3S
956905-27-4PF 04217903C19H16N8O
957054-33-02-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)thieno[3,2-d]pyrimidine methanesulfonate (1:2)C23H27N7O3S2.2(CH4O3S)


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