Category of chemicals: P38 MAPK inhibitor

P38 MAPK (Mitogen-Activated Protein Kinase) inhibitors are vital tools in the treatment of inflammatory diseases, as well as certain cancers. By blocking the activity of p38 MAPK, these inhibitors reduce the production of pro-inflammatory cytokines and chemokines, thus dampening the inflammatory response. This makes them essential in combating diseases such as rheumatoid arthritis and inflammatory bowel diseases. Researchers also explore their potential in cancer therapy as inflammation plays a role in tumor progression.

Products of P38 MAPK inhibitor
CAS No.	Product Name	Molecular Formula
1221485-83-1	Skepinone-L	C₂₄H₂₁F₂NO₄
152121-47-6	SB 203580	C₂₁H₁₆FN₃OS
209410-46-8	VX-745	C₁₉H₉Cl₂F₂N₃OS
285983-48-4	Doramapimod	C₃₁H₃₇N₅O₃
585543-15-3	6-[5-(Cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide	C₂₂H₂₆FN₃O₂
586379-66-0	PH 797804	C₂₂H₁₉BrF₂N₂O₃
745833-23-2	VX 702	C₁₉H₁₂F₄N₄O₂
862507-23-1	5-[2-(tert-Butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine methanesulfonate	C₂₄H₂₉FN₆.2(CH₄O₃S)

Products of P38 MAPK inhibitor

CAS No.

Product Name

Molecular Formula

1221485-83-1

Skepinone-L

C₂₄H₂₁F₂NO₄

152121-47-6

SB 203580

C₂₁H₁₆FN₃OS

209410-46-8

VX-745

C₁₉H₉Cl₂F₂N₃OS

285983-48-4

Doramapimod

C₃₁H₃₇N₅O₃

585543-15-3

6-[5-(Cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide

C₂₂H₂₆FN₃O₂

586379-66-0

PH 797804

C₂₂H₁₉BrF₂N₂O₃

745833-23-2

VX 702

C₁₉H₁₂F₄N₄O₂

862507-23-1

5-[2-(tert-Butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine methanesulfonate

C₂₄H₂₉FN₆.2(CH₄O₃S)