P-glycoprotein (P-gp) inhibitors are pharmaceutical compounds that play a critical role in cancer and infection treatment. These inhibitors prevent the expulsion of drugs by P-gp transporters, allowing higher drug concentrations to accumulate in target cells. This is particularly useful in overcoming drug resistance, a common problem in cancer and infectious disease treatment. By blocking P-gp activity, these inhibitors increase the effectiveness of medications and improve treatment outcomes.
