Category of chemicals: JAK inhibitor

Janus kinases (JAKs) are vital components of cytokine signaling pathways that regulate immune responses, hematopoiesis, and inflammation. JAK inhibitors are pharmacological agents that block JAK activity, offering a promising approach to treat conditions like rheumatoid arthritis, psoriasis, and certain cancers. By disrupting this pathway, JAK inhibitors help manage excessive immune responses and inflammatory processes. These drugs are a significant development in precision medicine, offering new hope to patients with autoimmune diseases and other conditions where JAK signaling plays a critical role.

Products of JAK inhibitor
CAS No.	Product Name	Molecular Formula
1021868-92-7	3-[(1-Methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-1-propanone hydrochloride	C₂₃H₂₅NO.HCl
1187594-09-7	Baricitinib	C₁₆H₁₇N₇O₂S
1206101-20-3	N-[5-[4-[(6-Cyano-3-pyridinyl)methoxy]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-cyclopropanecarboxamide	C₂₃H₁₈N₆O₂
1206161-97-8	N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide	C₂₁H₂₃N₅O₃S
1229236-86-5	LY 2784544	C₂₃H₂₅ClFN₇O
1257704-57-6	N-[3-(4-Methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine	C₂₄H₂₆N₆O₂S
1369761-01-2	Cerdulatinib hydrochloride	C₂₀H₂₈ClN₇O₃S
211555-04-3	4-(3'-Bromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline	C₁₆H₁₄BrN₃O₃
477600-75-2	CP 690550	C₁₆H₂₀N₆O
857064-38-1	WP 1066	C₁₇H₁₄BrN₃O
896466-04-9	1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea	C₁₉H₂₃N₇O₂
935666-88-9	AZD 1480	C₁₄H₁₄ClFN₈
936091-14-4	tg 101209	C₂₆H₃₅N₇O₂S
936091-26-8	TG 101348	C₂₇H₃₆N₆O₃S
937272-79-2	Pacritinib	C₂₈H₃₂N₄O₃
941685-37-6	S-Ruxolitinib	C₁₇H₁₈N₆
945755-56-6	(2S)-N-[4-[2-[[4-(4-Morpholinyl)phenyl]amino]-4-pyrimidinyl]phenyl]-2-pyrrolidinecarboxamide	C₂₅H₂₈N₆O₂

Products of JAK inhibitor

CAS No.

Product Name

Molecular Formula

1021868-92-7

3-[(1-Methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-1-propanone hydrochloride

C₂₃H₂₅NO.HCl

1187594-09-7

Baricitinib

C₁₆H₁₇N₇O₂S

1206101-20-3

N-[5-[4-[(6-Cyano-3-pyridinyl)methoxy]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-cyclopropanecarboxamide

C₂₃H₁₈N₆O₂

1206161-97-8

N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

C₂₁H₂₃N₅O₃S

1229236-86-5

LY 2784544

C₂₃H₂₅ClFN₇O

1257704-57-6

N-[3-(4-Methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine

C₂₄H₂₆N₆O₂S

1369761-01-2

Cerdulatinib hydrochloride

C₂₀H₂₈ClN₇O₃S

211555-04-3

4-(3'-Bromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline

C₁₆H₁₄BrN₃O₃

477600-75-2

CP 690550

C₁₆H₂₀N₆O

857064-38-1

WP 1066

C₁₇H₁₄BrN₃O

896466-04-9

1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea

C₁₉H₂₃N₇O₂

935666-88-9

AZD 1480

C₁₄H₁₄ClFN₈

936091-14-4

tg 101209

C₂₆H₃₅N₇O₂S

936091-26-8

TG 101348

C₂₇H₃₆N₆O₃S

937272-79-2

Pacritinib

C₂₈H₃₂N₄O₃

941685-37-6

S-Ruxolitinib

C₁₇H₁₈N₆

945755-56-6

(2S)-N-[4-[2-[[4-(4-Morpholinyl)phenyl]amino]-4-pyrimidinyl]phenyl]-2-pyrrolidinecarboxamide

C₂₅H₂₈N₆O₂

Category of Chemicals

JAK inhibitor