Category of Chemicals

IκB/IKK inhibitors are compounds that target the IκB/IKK pathway, a crucial signaling cascade involved in regulating the activation of NF-κB, a transcription factor central to immune and inflammatory responses. By inhibiting this pathway, these compounds can potentially suppress excessive inflammation and immune system activity, offering promising approaches for the treatment of autoimmune diseases and inflammatory disorders. However, careful consideration is needed to balance immune response modulation without compromising the body's ability to defend against infections and other external threats.