NOD1 inhibitors are compounds designed to target the NOD1 (Nucleotide-binding oligomerization domain-containing protein 1) pathway. NOD1 is a crucial component of the innate immune system, detecting bacterial pathogens and initiating immune responses. Inhibiting NOD1 can help regulate immune responses, particularly in conditions where excessive inflammation or immune system activity is problematic. These inhibitors are a focus of research for potential applications in autoimmune diseases and conditions where immune dysregulation plays a role. Careful development and testing are essential to ensure that they effectively modulate the immune response without causing harm.