Bendamustine Impurity 4
[CAS# 109882-30-6]

Identification

• Name: Bendamustine Impurity 4
• Synonyms: Dihydroxy Bendamustine;4-[5-[bis(2-hydroxyethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
• Molecular Formula: C₁₆H₂₃N₃O₄
• Molecular Weight: 321.37
• CAS Registry Number: 109882-30-6
• EC Number: 807-634-4
• SMILES: CN1C2=C(C=C(C=C2)N(CCO)CCO)N=C1CCCC(=O)O

Properties

• Solubility: 2146 mg/L (25 °C water)
• Density: 1.3±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.606, Calc.^*
• Melting point: 244.22 °C
• Boiling Point: 567.70 °C, 634.4±55.0 °C (760 mmHg), Calc.^*
• Flash Point: 337.5±31.5 °C, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS06;GHS08 Danger
• Risk Statements: H301-H340-H350-H360-H372
• Safety Statements: H301-H340-H350-H360-H372

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	3	H301
Carcinogenicity	Carc.	1A	H350
Specific target organ toxicity - repeated exposure	STOT RE	1	H372
Germ cell mutagenicity	Muta.	1B	H340
Reproductive toxicity	Repr.	1B	H360