Bendamustine Ethyl Ester
[CAS# 87475-54-5]

Identification

• Name: Bendamustine Ethyl Ester
• Synonyms: ethyl 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoate
• Molecular Formula: C₁₈H₂₅Cl₂N₃O₂
• Molecular Weight: 386.32
• CAS Registry Number: 87475-54-5
• EC Number: 800-121-6
• SMILES: CCOC(=O)CCCC1=NC2=C(N1C)C=CC(=C2)N(CCCl)CCCl

Properties

• Solubility: 0.1955 mg/L (25 °C water)
• Density: 1.2±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.570, Calc.^*
• Melting point: 222.64 °C
• Boiling Point: 521.50 °C, 545.7±50.0 °C (760 mmHg), Calc.^*
• Flash Point: 283.8±30.1 °C, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H302+H312+H332-H315-H319
• Safety Statements: P261-P271-P280-P302+P352-P305+P351+P338

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Reproductive toxicity	Repr.	1B	H360
Germ cell mutagenicity	Muta.	2	H341
Acute toxicity	Acute Tox.	3	H301
Skin irritation	Skin Irrit.	2	H315
Carcinogenicity	Carc.	2	H351