N-(Pyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
[CAS# 1383385-64-5]

Identification

• Classification: Organic raw materials >> Organoboron compounds
• Name: N-(Pyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
• Molecular Formula: C₁₈H₂₁BN₂O₃
• Molecular Weight: 324.18
• CAS Registry Number: 1383385-64-5
• EC Number: 817-663-4
• SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)C(=O)NC3=CC=CC=N3

Properties

• Density: 1.16±0.1 g/cm³ (20 °C 760 Torr), Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2016 ACD/Labs)

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H302-H315-H319-H335
• Safety Statements: P261-P305+P351+P338

Discovery and Applications

N-(pyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide is a complex organic compound that has been applied in various fields of chemical and biological research. Its structure combines a pyridine ring, a benzamide group, and a boronate ester, giving it unique properties that can be used in a variety of applications.

The compound was developed through targeted synthetic efforts to combine the reactivity of boronate esters with the stability and functionality of benzamide derivatives. The introduction of a pyridine ring in the structure is intended to enhance the ability of the compound to interact with biological targets or act as a ligand in chemical reactions. The synthesis involves advanced organic chemistry techniques to create the desired functional groups and integrate them into a single molecular framework.

In organic synthesis, the compound serves as a versatile building block for the creation of complex molecules. Its boronate ester group can participate in the Suzuki-Miyaura cross-coupling reaction, a powerful method for forming carbon-carbon bonds. This property makes it valuable in the synthesis of pharmaceuticals, agrochemicals, and advanced materials.

The benzamide and pyridine moieties of the compound make it a candidate for drug discovery and development. Due to its ability to interact with a variety of biological targets, researchers are investigating its potential as a pharmaceutical agent. Its boronate group also provides opportunities to design inhibitors or modulators of specific enzymes or receptors.

The boronate group in this compound can be used for molecular imaging. Its unique chemical properties can be used to develop imaging probes that can selectively bind to biological targets, helping to visualize specific cellular processes or disease states.

This compound is being studied for its potential use as a catalyst in various chemical reactions. Its boronate functionality can enhance the reactivity of catalytic systems for the synthesis of complex organic compounds.

References

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