Xylidyl blue I
[CAS# 14936-97-1]

Identification

• Classification: Organic raw materials >> Organometallic compound >> Organic sodium
• Name: Xylidyl blue I
• Synonyms: Sodium 3-[[3-[(2,4-dimethylphenyl)carbamoyl]-2-hydroxynaphthalen-1-yl]diazenyl]-4-hydroxybenzenesulfonate
• Molecular Formula: C₂₅H₂₀N₃NaO₆S
• Molecular Weight: 513.50
• CAS Registry Number: 14936-97-1
• EC Number: 239-012-8
• SMILES: CC1=CC(=C(C=C1)NC(=O)C2=CC3=CC=CC=C3C(=C2O)N=NC4=C(C=CC(=C4)S(=O)(=O)[O-])O)C.[Na+]

Discovery and Applications

Xylidyl blue I, a chemical dye with the formula C₁₆H₁₈ClN₃O, has made significant contributions to various fields since its discovery. First synthesized in the early 20th century, this compound is notable for its vivid blue color and its applications in both biological staining and industrial processes.

The discovery of Xylidyl blue I emerged from the broader efforts to develop synthetic dyes, a field that expanded rapidly with the advent of industrial chemistry. The dye was initially developed for its vibrant hue and stability, which made it a valuable addition to the palette of synthetic dyes available at the time. Its chemical structure features a xylidyl group, which is integral to its blue coloration and chemical properties.

In biological and medical research, Xylidyl blue I is primarily used as a histological stain. Its utility in staining tissues and cells allows for enhanced visualization under a microscope, which is crucial for studying tissue structure, identifying cellular components, and diagnosing pathological conditions. The dye binds selectively to certain cellular structures, thereby differentiating them from the surrounding areas. This selective staining is valuable in medical diagnostics and research, facilitating a clearer understanding of cellular morphology and pathology.

Beyond its use in biological staining, Xylidyl blue I has applications in various industrial sectors. In the textile industry, it is used as a dye for fabrics, providing a stable and vibrant blue color that withstands washing and light exposure. Its properties make it suitable for dyeing a range of materials, contributing to the aesthetics and functionality of textile products. Additionally, Xylidyl blue I is utilized in the printing industry, where its vibrant color is employed in inks and coatings, enhancing the visual appeal and quality of printed materials.

Despite its versatility, the use of Xylidyl blue I, like many synthetic dyes, necessitates careful handling due to potential environmental and health considerations. The chemical’s impact on ecosystems and human health requires adherence to safety regulations and practices. Proper disposal and management of waste containing this dye are essential to mitigate any adverse effects associated with its use.

References

1986. Measurement of magnesium in serum and urine with a random access analyzer by use of a modified xylidyl blue-1 procedure. Clinica Chimica Acta, 159(2).
DOI: 10.1016/0009-8981(86)90052-5

1990. Determination of Urine Magnesium Using the Magon Dye Method on the 'Monarch' Centrifugal Analyser. Annals of Clinical Biochemistry, 27(6).
DOI: 10.1177/000456329002700612

1996. Validation of an enzymatic total magnesium determination based on activation of modified isocitrate dehydrogenase. Clinical Chemistry, 42(9).
DOI: 10.1093/clinchem/42.9.1474