Pirtobrutinib
[CAS# 2101700-15-4]

Identification

• Classification: Biochemical >> Inhibitor >> Angiogenesis >> BTK inhibitor
• Name: Pirtobrutinib
• Synonyms: 5-amino-3-[4-[[(5-fluoro-2-methoxybenzoyl)amino]methyl]phenyl]-1-[(2S)-1,1,1-trifluoropropan-2-yl]pyrazole-4-carboxamide
• Molecular Formula: C₂₂H₂₁F₄N₅O₃
• Molecular Weight: 479.43
• CAS Registry Number: 2101700-15-4
• EC Number: 864-730-9
• SMILES: C[C@@H](C(F)(F)F)N1C(=C(C(=N1)C2=CC=C(C=C2)CNC(=O)C3=C(C=CC(=C3)F)OC)C(=O)N)N

Properties

• Density: 1.4±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.598, Calc.^*
• Boiling Point: 619.2±55.0 °C (760 mmHg), Calc.^*
• Flash Point: 328.3±31.5 °C, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS08;GHS09 Danger
• Risk Statements: H360-H373-H411
• Safety Statements: P203-P260-P273-P280-P318-P319-P391-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Specific target organ toxicity - repeated exposure	STOT RE	2	H373
Reproductive toxicity	Repr.	1B	H360
Chronic hazardous to the aquatic environment	Aquatic Chronic	2	H411