4-Bromo-3,3,4,4-tetrafluorobutan-1-ol
[CAS# 234443-21-1]

Identification

• Classification: Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Pyrimidine compound >> Alcohol
• Name: 4-Bromo-3,3,4,4-tetrafluorobutan-1-ol
• Molecular Formula: C₄H₅BrF₄O
• Molecular Weight: 224.98
• CAS Registry Number: 234443-21-1
• SMILES: C(CO)C(C(F)(F)Br)(F)F

Properties

• Boiling point: 70 °C (30 mmHg)

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H302-H315-H319-H335
• Safety Statements: P261-P305+P351+P338

Discovery and Applications

4-Bromo-3,3,4,4-tetrafluorobutan-1-ol is a fluorinated organic compound notable for its unique combination of bromine and fluorine atoms, which imparts distinctive chemical and physical properties. The discovery of this compound stems from the broader study of halogenated alcohols, which are valuable in various chemical synthesis applications due to their reactivity and stability.

This compound's structure, featuring both bromine and fluorine substituents, makes it an important intermediate in organic synthesis. The presence of fluorine atoms provides significant stability and resistance to chemical degradation, while the bromine atom introduces reactive sites for further transformations. This dual functionality allows 4-bromo-3,3,4,4-tetrafluorobutan-1-ol to serve as a versatile building block in the creation of more complex molecules.

One of the primary applications of this compound is in the synthesis of pharmaceuticals and agrochemicals. Fluorinated alcohols like 4-bromo-3,3,4,4-tetrafluorobutan-1-ol are used to modify the properties of drug candidates, enhancing their efficacy and metabolic stability. The bromine atom can facilitate specific reactions or act as a point for further chemical modifications, making it valuable in designing new therapeutic agents.

In material science, this compound can be utilized to develop specialty polymers and materials with tailored properties. The incorporation of fluorine into polymers can enhance their chemical resistance, thermal stability, and surface characteristics. These materials are used in high-performance coatings, electronic components, and protective films, where durability and resistance to harsh conditions are crucial.

Additionally, 4-bromo-3,3,4,4-tetrafluorobutan-1-ol can be employed in the development of novel reagents and catalysts for organic reactions. Its unique combination of bromine and fluorine enables it to participate in various chemical processes, offering opportunities for innovation in synthetic chemistry.

References

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