4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]quinoline
[CAS# 396129-53-6]

Identification

• Classification: Biochemical >> Inhibitor >> TGF-beta/Smad signaling pathway inhibitor (TGF-beta/Smad) >> TGF-beta/Smad inhibitor
• Name: 4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]quinoline
• Synonyms: E 616451; HTS 466284; LY 364947
• Molecular Formula: C₁₇H₁₂N₄
• Molecular Weight: 272.30
• CAS Registry Number: 396129-53-6
• EC Number: 636-801-2

Properties

• Solubility: Practically insoluble (0.013 g/L) (25 °C), Calc.^*
• Density: 1.283±0.06 g/cm³ (20 °C 760 Torr), Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2013 ACD/Labs)

Safety Data

• Hazard Symbols: T;N
• Risk Statements: R25;R36/37/38;R50/53
• Safety Statements: S26;S45;S60;S61

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Skin irritation	Skin Irrit.	2	H315
Specific target organ toxicity - single exposure	STOT SE	3	H335
Eye irritation	Eye Irrit.	2	H319
Acute toxicity	Acute Tox.	3	H301
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400
Acute toxicity	Acute Tox.	4	H332
Acute toxicity	Acute Tox.	4	H312
Acute toxicity	Acute Tox.	4	H302

• Transport Information: UN 2811 6.1/PG 3